
Life Science Buffers
Balanced salt solutions and powders used for molecular, protein, nucleic acid, and cell biology applications including cell culture, electrophoresis, ELISA, and chromatography processes; available in a variety of formulations and grades.
Buffer solutions serve to keep pH (acidity or alkalinity) nearly constant in a variety of chemical and biological applications. For example, a bicarbonate buffer helps maintain the pH of blood, a buffered saline maintains cellular contents at a consistent pH level, and buffers help maintain a narrow pH range for enzymes to function correctly.
Most biological samples used in research are kept at a pH of about 7.4. Common biological buffers used for tissue culture include Dulbeccos phosphate buffered saline (PBS), Tris base, HEPES, MOPS, PIPES, and other formulations developed for specific cell lines or applications. Most buffers used in cell culture are also DNase-, RNase-, and protease-free.
The choice of buffer for a particular biological reaction or site depends on several factors:
- Temperature
- Desired or target pH
- Buffer toxicity (to the system)
- Buffer interactions with other system components
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Filtered Search Results

MilliporeSigma™ HEPES, Free Acid, ULTROL™ Grade, Calbiochem™,
CAS: 7365-45-9 Molecular Formula: C8H18N2O4S Molecular Weight (g/mol): 238.30 MDL Number: MFCD00006158 InChI Key: JKMHFZQWWAIEOD-UHFFFAOYSA-N Synonym: N-2-Hydroxyethylpiperazine-N'-2-ethanesulfonic Acid PubChem CID: 23831 ChEBI: CHEBI:42334 IUPAC Name: 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid SMILES: OCCN1CCN(CCS(O)(=O)=O)CC1
PubChem CID | 23831 |
---|---|
CAS | 7365-45-9 |
Molecular Weight (g/mol) | 238.30 |
ChEBI | CHEBI:42334 |
MDL Number | MFCD00006158 |
SMILES | OCCN1CCN(CCS(O)(=O)=O)CC1 |
Synonym | N-2-Hydroxyethylpiperazine-N'-2-ethanesulfonic Acid |
IUPAC Name | 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid |
InChI Key | JKMHFZQWWAIEOD-UHFFFAOYSA-N |
Molecular Formula | C8H18N2O4S |
MilliporeSigma™ Bicine, ULTROL™ Grade, Calbiochem™,
CAS: 150-25-4 Molecular Formula: C6H12NNaO4 Molecular Weight (g/mol): 185.16 MDL Number: MFCD00004295 InChI Key: MFBDBXAVPLFMNJ-UHFFFAOYSA-M Synonym: N,N-bis-(2-Hydroxyethyl)glycine PubChem CID: 8761 ChEBI: CHEBI:40957 IUPAC Name: sodium 2-[bis(2-hydroxyethyl)amino]acetate SMILES: [Na+].OCCN(CCO)CC([O-])=O
PubChem CID | 8761 |
---|---|
CAS | 150-25-4 |
Molecular Weight (g/mol) | 185.16 |
ChEBI | CHEBI:40957 |
MDL Number | MFCD00004295 |
SMILES | [Na+].OCCN(CCO)CC([O-])=O |
Synonym | N,N-bis-(2-Hydroxyethyl)glycine |
IUPAC Name | sodium 2-[bis(2-hydroxyethyl)amino]acetate |
InChI Key | MFBDBXAVPLFMNJ-UHFFFAOYSA-M |
Molecular Formula | C6H12NNaO4 |
Invitrogen™ xMAP Sheath Fluid Plus
xMAP Sheath Fluid Plus is the delivery medium that carries the sample to the optics component of Luminex xMAP technology-based instruments

Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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MOPSO Sodium Salt, MP Biomedicals™
CAS: 79803-73-9 Molecular Formula: C7H14NNaO5S Molecular Weight (g/mol): 247.24 InChI Key: WSFQLUVWDKCYSW-UHFFFAOYNA-M IUPAC Name: sodium 2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonate SMILES: [Na+].OC(CN1CCOCC1)CS([O-])(=O)=O
CAS | 79803-73-9 |
---|---|
Molecular Weight (g/mol) | 247.24 |
SMILES | [Na+].OC(CN1CCOCC1)CS([O-])(=O)=O |
IUPAC Name | sodium 2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonate |
InChI Key | WSFQLUVWDKCYSW-UHFFFAOYNA-M |
Molecular Formula | C7H14NNaO5S |
Tris, Cell Culture Reagent, ≥99.95%, MP Biomedicals™
Tris, Cell Culture Reagent, ≥99.95% is a biological buffer for various applications.
Gibco™ DPBS, powder, calcium, magnesium
Dulbecco's Phosphate-Buffered Saline (DPBS) is a balanced salt solution used for a variety of cell culture applications, such as washing cells before dissociation, transporting cells or tissue, diluting cells for counting, and preparing reagents.

Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Includes | No Sodium Pyruvate |
---|---|
Physical Form | Powder |
Manufacturing Quality | cGMP-compliant under the ISO 13485 standard |
Chemical Name or Material | DPBS |
For Use With (Application) | Mammalian Cell Culture |
Solution Type | Dulbecco's Phosphate Buffered Saline |
Product Line | Gibco™ |
POPSO, 0.2M buffer soln., pH 8.0, Thermo Scientific™
CAS: 108321-07-9 Molecular Formula: C10H20N2Na2O8S2 Molecular Weight (g/mol): 406.376 MDL Number: MFCD00070005 InChI Key: XMRCLLXGMGEVHS-UHFFFAOYSA-L PubChem CID: 53393457 IUPAC Name: disodium;2-hydroxy-3-[4-(2-hydroxy-3-sulfonatopropyl)piperazin-1-yl]propane-1-sulfonate SMILES: C1CN(CCN1CC(CS(=O)(=O)[O-])O)CC(CS(=O)(=O)[O-])O.[Na+].[Na+]
PubChem CID | 53393457 |
---|---|
CAS | 108321-07-9 |
Molecular Weight (g/mol) | 406.376 |
MDL Number | MFCD00070005 |
SMILES | C1CN(CCN1CC(CS(=O)(=O)[O-])O)CC(CS(=O)(=O)[O-])O.[Na+].[Na+] |
IUPAC Name | disodium;2-hydroxy-3-[4-(2-hydroxy-3-sulfonatopropyl)piperazin-1-yl]propane-1-sulfonate |
InChI Key | XMRCLLXGMGEVHS-UHFFFAOYSA-L |
Molecular Formula | C10H20N2Na2O8S2 |
MDL Number | MFCD00131625 |
---|---|
Physical Form | Liquid |
Health Hazard 1 | H335 |
Chemical Name or Material | MOPS-EDTA-sodium acetate buffer (MESA) |
TSCA | Yes |
Recommended Storage | Ambient temperatures |
Thermo Scientific Chemicals Potassium phosphate, 0.5M buffer soln., pH 7.2
CAS: 7778-77-0 Molecular Formula: H2KO4P Molecular Weight (g/mol): 136.08 MDL Number: MFCD00011401 MFCD00147253 InChI Key: GNSKLFRGEWLPPA-UHFFFAOYSA-M IUPAC Name: potassium dihydrogen phosphate SMILES: [K+].OP(O)([O-])=O
CAS | 7778-77-0 |
---|---|
Molecular Weight (g/mol) | 136.08 |
MDL Number | MFCD00011401 MFCD00147253 |
SMILES | [K+].OP(O)([O-])=O |
IUPAC Name | potassium dihydrogen phosphate |
InChI Key | GNSKLFRGEWLPPA-UHFFFAOYSA-M |
Molecular Formula | H2KO4P |
Thermo Scientific Chemicals CAPS, 0.5M buffer soln., pH 10.0
CAS: 1135-40-6 Molecular Formula: C9H19NO3S Molecular Weight (g/mol): 221.32 MDL Number: MFCD00003837 InChI Key: PJWWRFATQTVXHA-UHFFFAOYSA-N IUPAC Name: 3-(cyclohexylamino)propane-1-sulfonic acid SMILES: OS(=O)(=O)CCCNC1CCCCC1
CAS | 1135-40-6 |
---|---|
Molecular Weight (g/mol) | 221.32 |
MDL Number | MFCD00003837 |
SMILES | OS(=O)(=O)CCCNC1CCCCC1 |
IUPAC Name | 3-(cyclohexylamino)propane-1-sulfonic acid |
InChI Key | PJWWRFATQTVXHA-UHFFFAOYSA-N |
Molecular Formula | C9H19NO3S |
Thermo Scientific Chemicals PIPES, 1.0M buffer soln., pH 8.0
CAS: 5625-37-6 Molecular Formula: C8H18N2O6S2 Molecular Weight (g/mol): 302.36 MDL Number: MFCD00006159 InChI Key: IHPYMWDTONKSCO-UHFFFAOYSA-N PubChem CID: 79723 ChEBI: CHEBI:44933 IUPAC Name: 2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonic acid SMILES: C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)O
PubChem CID | 79723 |
---|---|
CAS | 5625-37-6 |
Molecular Weight (g/mol) | 302.36 |
ChEBI | CHEBI:44933 |
MDL Number | MFCD00006159 |
SMILES | C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)O |
IUPAC Name | 2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonic acid |
InChI Key | IHPYMWDTONKSCO-UHFFFAOYSA-N |
Molecular Formula | C8H18N2O6S2 |
Thermo Scientific Chemicals ACES Buffer (0.5 M, pH 7.0)
CAS: 7365-82-4 Molecular Formula: C4H10N2O4S Molecular Weight (g/mol): 182.194 MDL Number: MFCD00008030 InChI Key: DBXNUXBLKRLWFA-UHFFFAOYSA-N PubChem CID: 81832 ChEBI: CHEBI:39062 IUPAC Name: 2-[(2-amino-2-oxoethyl)amino]ethanesulfonic acid SMILES: C(CS(=O)(=O)O)NCC(=O)N
PubChem CID | 81832 |
---|---|
CAS | 7365-82-4 |
Molecular Weight (g/mol) | 182.194 |
ChEBI | CHEBI:39062 |
MDL Number | MFCD00008030 |
SMILES | C(CS(=O)(=O)O)NCC(=O)N |
IUPAC Name | 2-[(2-amino-2-oxoethyl)amino]ethanesulfonic acid |
InChI Key | DBXNUXBLKRLWFA-UHFFFAOYSA-N |
Molecular Formula | C4H10N2O4S |
Name Note | low salt |
---|---|
Color | Colorless |
Solubility Information | Fully misicible in water. |
Physical Form | Liquid |
Chemical Name or Material | NP-40 lysis buffer |
TSCA | Yes |
Recommended Storage | Keep cold |
Thermo Scientific Chemicals HEPES-buffered saline, pH 7.0 (5X)
CAS: 7365-45-9 Molecular Formula: C8H18N2O4S Molecular Weight (g/mol): 238.30 MDL Number: MFCD00006158 InChI Key: JKMHFZQWWAIEOD-UHFFFAOYSA-N PubChem CID: 23831 ChEBI: CHEBI:42334 IUPAC Name: 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid SMILES: OCCN1CCN(CCS(O)(=O)=O)CC1
PubChem CID | 23831 |
---|---|
CAS | 7365-45-9 |
Molecular Weight (g/mol) | 238.30 |
ChEBI | CHEBI:42334 |
MDL Number | MFCD00006158 |
SMILES | OCCN1CCN(CCS(O)(=O)=O)CC1 |
IUPAC Name | 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid |
InChI Key | JKMHFZQWWAIEOD-UHFFFAOYSA-N |
Molecular Formula | C8H18N2O4S |