Life Science Buffers

Balanced salt solutions and powders used for molecular, protein, nucleic acid, and cell biology applications including cell culture, electrophoresis, ELISA, and chromatography processes; available in a variety of formulations and grades.

Buffer solutions serve to keep pH (acidity or alkalinity) nearly constant in a variety of chemical and biological applications. For example, a bicarbonate buffer helps maintain the pH of blood, a buffered saline maintains cellular contents at a consistent pH level, and buffers help maintain a narrow pH range for enzymes to function correctly.

Most biological samples used in research are kept at a pH of about 7.4. Common biological buffers used for tissue culture include Dulbeccos phosphate buffered saline (PBS), Tris base, HEPES, MOPS, PIPES, and other formulations developed for specific cell lines or applications. Most buffers used in cell culture are also DNase-, RNase-, and protease-free.

The choice of buffer for a particular biological reaction or site depends on several factors:

Temperature
Desired or target pH
Buffer toxicity (to the system)
Buffer interactions with other system components

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451 – 465 of 3,516 results

451

Thermo Scientific Chemicals TBE (5X), TRIS + borate + EDTA

Pricing & Availability
Specifications

MDL Number	MFCD00236358
Packaging	Plastic bottle
Physical Form	Liquid
Chemical Name or Material	TBE (5X)
TSCA	Yes
Recommended Storage	Ambient temperatures

452

Thermo Scientific Chemicals Hanks' Balanced Salt Solution (1X), with calcium, with magnesium, with phenol red

Pricing & Availability
Specifications

Color	Red
Physical Form	Liquid
Recommended Storage	Ambient temperatures

453

Thermo Scientific Chemicals LDS-sample buffer (4X), non-reducing

Pricing & Availability
Specifications

Color	Blue
Physical Form	Liquid
Recommended Storage	Ambient temperatures
Concentration	4X

454

Corning™ Mediatech™ Cell Culture Phosphate Buffered Saline (10X)

With low endotoxin content

Pricing & Availability

455

Thermo Scientific Chemicals HEPES-buffered saline (2X, pH 7.0), low endotoxin

Pricing & Availability
Specifications

Name Note	low endotoxin
Storage Note 1	2° to 8°C
Color	Colorless
Physical Form	Liquid
Chemical Name or Material	HEPES-buffered saline (2X, pH 7.0)
TSCA	Yes
Recommended Storage	Keep cold

456

Tris Hydrochloride, >99%, Reagent grade, MP Biomedicals™

CAS: 1185-53-1 Molecular Formula: C4H12ClNO3 Molecular Weight (g/mol): 157.594 MDL Number: MFCD00012590 InChI Key: QKNYBSVHEMOAJP-UHFFFAOYSA-N Synonym: Trometamol,Tromethamine PubChem CID: 93573 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride SMILES: C(C(CO)(CO)N)O.Cl

Pricing & Availability
Specifications

PubChem CID	93573
CAS	1185-53-1
Molecular Weight (g/mol)	157.594
MDL Number	MFCD00012590
SMILES	C(C(CO)(CO)N)O.Cl
Synonym	Trometamol,Tromethamine
IUPAC Name	2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride
InChI Key	QKNYBSVHEMOAJP-UHFFFAOYSA-N
Molecular Formula	C4H12ClNO3

457

Glycylglycine, 0.2M buffer soln., pH 8.0, Thermo Scientific™

CAS: 556-50-3 Molecular Formula: C4H8N2O3 Molecular Weight (g/mol): 132.119 MDL Number: MFCD00008130 InChI Key: YMAWOPBAYDPSLA-UHFFFAOYSA-N PubChem CID: 11163 ChEBI: CHEBI:17201 IUPAC Name: 2-[(2-aminoacetyl)amino]acetic acid SMILES: C(C(=O)NCC(=O)O)N

Pricing & Availability
Specifications

PubChem CID	11163
CAS	556-50-3
Molecular Weight (g/mol)	132.119
ChEBI	CHEBI:17201
MDL Number	MFCD00008130
SMILES	C(C(=O)NCC(=O)O)N
IUPAC Name	2-[(2-aminoacetyl)amino]acetic acid
InChI Key	YMAWOPBAYDPSLA-UHFFFAOYSA-N
Molecular Formula	C4H8N2O3

458

Thermo Scientific Chemicals TRIS, 1.0M buffer soln., pH 8.5, 0.2 micron filtered

CAS: 77-86-1 Molecular Formula: C4H11NO3 Molecular Weight (g/mol): 121.136 MDL Number: MFCD00004679 InChI Key: LENZDBCJOHFCAS-UHFFFAOYSA-N PubChem CID: 6503 ChEBI: CHEBI:9754 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol SMILES: C(C(CO)(CO)N)O

Pricing & Availability
Specifications

PubChem CID	6503
CAS	77-86-1
Molecular Weight (g/mol)	121.136
ChEBI	CHEBI:9754
MDL Number	MFCD00004679
SMILES	C(C(CO)(CO)N)O
IUPAC Name	2-amino-2-(hydroxymethyl)propane-1,3-diol
InChI Key	LENZDBCJOHFCAS-UHFFFAOYSA-N
Molecular Formula	C4H11NO3

459

MilliporeSigma™ PIPES, Sodium Salt, Molecular biology grade, OmniPur™, Calbiochem™,

CAS: 100037-69-2 Molecular Formula: C16H33N4Na3O12S4 Molecular Weight (g/mol): 670.665 InChI Key: FPDACHMSOMILQI-UHFFFAOYSA-K PubChem CID: 3086462 IUPAC Name: trisodium;2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonate;2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethanesulfonate SMILES: C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)[O-].C1CN(CCN1CCS(=O)(=O)[O-])CCS(=O)(=O)[O-].[Na+].[Na+].[Na+]

Pricing & Availability
Specifications

PubChem CID	3086462
CAS	100037-69-2
Molecular Weight (g/mol)	670.665
SMILES	C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)[O-].C1CN(CCN1CCS(=O)(=O)[O-])CCS(=O)(=O)[O-].[Na+].[Na+].[Na+]
IUPAC Name	trisodium;2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonate;2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethanesulfonate
InChI Key	FPDACHMSOMILQI-UHFFFAOYSA-K
Molecular Formula	C16H33N4Na3O12S4

460

MilliporeSigma™ MOPS, Sodium, ULTROL™ Grade, Calbiochem™,

CAS: 71119-22-7 Molecular Formula: C7H14NNaO4S Molecular Weight (g/mol): 231.242 InChI Key: MWEMXEWFLIDTSJ-UHFFFAOYSA-M Synonym: 3-(N-Morpholino)propanesulfonic Acid, Na PubChem CID: 3859613 IUPAC Name: sodium;3-morpholin-4-ylpropane-1-sulfonate SMILES: C1COCCN1CCCS(=O)(=O)[O-].[Na+]

Pricing & Availability
Specifications

PubChem CID	3859613
CAS	71119-22-7
Molecular Weight (g/mol)	231.242
SMILES	C1COCCN1CCCS(=O)(=O)[O-].[Na+]
Synonym	3-(N-Morpholino)propanesulfonic Acid, Na
IUPAC Name	sodium;3-morpholin-4-ylpropane-1-sulfonate
InChI Key	MWEMXEWFLIDTSJ-UHFFFAOYSA-M
Molecular Formula	C7H14NNaO4S

461

Tris Hydrochloride, MP Biomedicals™

Molecular Formula: C4H12ClNO3 Molecular Weight (g/mol): 157.594 InChI Key: QKNYBSVHEMOAJP-UHFFFAOYSA-N Synonym: Trometamol, Tromethamine, Tris-[hydroxymethyl]aminomethane, 2-Amino-2-(hydroxymethyl)-1,3-propanediol PubChem CID: 93573 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride SMILES: C(C(CO)(CO)N)O.Cl

Pricing & Availability
Specifications

PubChem CID	93573
Molecular Weight (g/mol)	157.594
SMILES	C(C(CO)(CO)N)O.Cl
Synonym	Trometamol, Tromethamine, Tris-[hydroxymethyl]aminomethane, 2-Amino-2-(hydroxymethyl)-1,3-propanediol
IUPAC Name	2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride
InChI Key	QKNYBSVHEMOAJP-UHFFFAOYSA-N
Molecular Formula	C4H12ClNO3

462

Thermo Scientific Chemicals TRIS-buffered saline (TBS, 10X), with 1% Tween 20

Pricing & Availability
Specifications

Physical Form	Liquid
Recommended Storage	Ambient temperatures
Concentration	10X

463

MP Biomedicals™ PBS 10X

PBS 10X, Rnase, Dnase, Protease free, Filtered through 0,2μm PTFE.

Pricing & Availability

464

AMP, 0.2M buffer soln., pH 9.5, Thermo Scientific™

Pricing & Availability
Specifications

Molecular Weight (g/mol)	89.14
Color	Colorless
Physical Form	Liquid
SMILES	CC(C)(N)CO
Concentration	0.2 M
InChI Key	CBTVGIZVANVGBH-UHFFFAOYSA-N
CAS	124-68-5
MDL Number	MFCD00008051
pH	9.5
Synonym	2-Amino-2-methyl-1-propanol
Recommended Storage	Keep cold
IUPAC Name	2-amino-2-methylpropan-1-ol
Molecular Formula	C4H11NO
Odor	Odorless

465

MilliporeSigma™ TRIS Hydrochloride, OmniPur™, Calbiochem™,

CAS: 1185-53-1 Molecular Formula: C4H12ClNO3 Molecular Weight (g/mol): 157.594 InChI Key: QKNYBSVHEMOAJP-UHFFFAOYSA-N Synonym: Trizma, Tris(hydroxymethyl)aminomethane PubChem CID: 93573 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride SMILES: C(C(CO)(CO)N)O.Cl

Pricing & Availability
Specifications

PubChem CID	93573
CAS	1185-53-1
Molecular Weight (g/mol)	157.594
SMILES	C(C(CO)(CO)N)O.Cl
Synonym	Trizma, Tris(hydroxymethyl)aminomethane
IUPAC Name	2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride
InChI Key	QKNYBSVHEMOAJP-UHFFFAOYSA-N
Molecular Formula	C4H12ClNO3

Life Science Buffers

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Corning™ Mediatech™ Cell Culture Phosphate Buffered Saline (10X) GSA/VA ContractAvailable on GSA/VA contract for Federal Government customers.Learn More Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Corning™ Mediatech™ Cell Culture Phosphate Buffered Saline (10X)